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DBM feels that it is established enough and skilled enough in the art and the science of Humanized Drug Discovery to offer this page so as to have interested customers inquire about a custom program that DBM could fulfill, working together with the client.
Examples of Custom Programs in Recent Years:
- Primary human cell culture establishment and human cell immortalization and cell line creation
- Primary mouse cell culture establishment and mouse cell immortalization and cell line creation
- Hit-to-lead and lead asset testing on normal and ADPKD human kidney cells
- Targeted high-throughput screening in 3D or 2D formats w/ human lung, renal, and vascular cells
- Hit-to-lead and lead asset testing with a panel of bioassays in differentiated human adipocytes and other human cells relevant to metabolic diseases
- HTS and validation using ion-sensitive fluorescent probes or voltage-sensitive dyes in intact, living cells at physiological temperatures and in real time